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Specifications
- Antibody Type:Primary
- Antigen Name:MAP3K9
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG (H, L)
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:100 µl
- Environmentally Preferable:
- Gene ID:4293
- Storage Buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- Molecular Weight:122
- Storage Temperature:Shipped at 4 ℃. Store at −20 °C for one year. Avoid repeated freeze/thaw cycles.
- Concentration:1 µg/µl
- Purification:Purified by Protein A
- Cat. No.:77436-866
- Packaging:Vial
Specifications
About this item
Mixed lineage kinases are a family of protein kinases sharing two leucine zipper-like motifs, which are known to mediate protein dimerization, and a kinase domain whose primary structure is similar to both the tyrosine-specific and the serine/threonine-specific kinase classes. Members of the mixed-lineage kinase (MLK) family include MLK1, MLK2, MLK3 and dual leucine zipper kinase, also designated DLK. MLKs are expressed in neuronal cells where they are likely to interact between Rac1/Cdc42, MKK4 and MKK7 in death signaling. The human MLK1 gene maps to chromosome 14q24.3-q31 and is expressed in epithelial tumor cell lines of the colon, breast, and esophagus. The human MLK2 gene maps to chromosome 19 q13.2. and encodes a predicted 954 amino acid, src homology 3 (SH3) domain-containing protein. The human MLK3 gene maps to chromosome 11q13.1-13.3 and encodes a 847 amino acid, SH3 domain- and proline rich region-containing protein. Apoptosis mechanisms rely on MLKs as an upstream intermediate of mitochondrial cytochrome c release and caspase activation.
Type: Primary
Antigen: MAP3K9
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human, Mouse