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Anti-p150 CAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-p150 CAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76107-678
Supplier:  Bioss
Anti-p150 CAF1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76107-678
Supplier:  Bioss
Supplier Number:  BS-9392R-A750

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    p150 CAF1
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    100 µl
  • Epitope:
    355-450/956
  • Form:
    Liquid
  • Gene ID:
    10036
  • Antigen Synonyms:
    NURF150|CAF1 subunit A|CAF1P150|CAF|CAF1P155|CHAF1A|CAF I 150 kDa subunit|CAF 1 150 kDa subunit|CAF 1 subunit A|CAF-1 p150|CAF-1 subunit A|hp150|Chromatin Assembly Factor I|CAF-I p150|CAF1 p150 Subunit|CAF1B|CAF-I 150 kDa subunit|Chromatin assembly factor I p150 subunit|DCAF1|CAF 1|CAF1 150 kDa subunit|Nucleosome Remodeling Factor 150kDa Subunit|Chromatin assembly factor I 150 kDa|Chromatin Assembly Factor 1 Subunit A p150|CAF1A|P150|CAF Ip150|CAF1|CAF I p150|Chromatin assembly factor 1 subunit A|CAF1A_HUMAN
  • Modification:
    Unmodified
  • Storage Buffer:
    Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
  • Storage Temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping Temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human p150 CAF1
  • Purification:
    Purified by Protein A
  • Cat. No.:
    76107-678
  • Packaging:
    Vial

Specifications

About this item

Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Type: Primary
Antigen: p150 CAF1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 355-450/956
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat