Specifications
- Antibody Type:Primary
- Antigen Name:beta 2 Defensin
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Size:100 µl
- Epitope:24-64/64
- Form:Liquid
- Gene ID:1673
- Antigen Synonyms:DEFB2|BD-2|DEFB4A|Beta-defensin 4A|SAP1|DEFB4|Defensin, beta 2|Skin-antimicrobial peptide 1|DEFB-2|Beta-defensin 2|HBD-2|DEFB12
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Molecular Weight:4 kDa
- Storage Temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human beta 2 Defensin
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76078-790
- Packaging:Vial
Specifications
About this item
Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways.
Type: Primary
Antigen: beta 2 Defensin
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 24-64/64
Host: Rabbit
Isotype: IgG
Reactivity: Rat