Specifications
- Antibody Type:Primary
- Antigen Name:CETP
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western Blot:Yes
- Size:100 µl
- Epitope:355-450/493
- Form:Liquid
- Gene ID:1071
- Antigen Synonyms:Cholesteryl ester transfer protein precursor|BPF|Cholesteryl ester transfer protein|Cholesteryl ester transfer|HDLCQ10|CETP|CETP_HUMAN|Cholesteryl ester transfer protein plasma|Lipid transfer protein I
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Molecular Weight:53 kDa
- Storage Temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CETP
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76084-738
- Packaging:Vial
Specifications
About this item
High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
Type: Primary
Antigen: CETP
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 355-450/493
Host: Rabbit
Isotype: IgG
Reactivity: Mouse