Collagen IV is a ubiquitous component of basement membranes. It plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation. Corning® BioCoat™ Collagen IV flasks are tissue culture vessels with a uniform application of mouse collagen type IV. These flasks are manufactured in a highly controlled environment and are rigorously tested to assure product consistency and performance.

Applications include promotion of cell attachment and spreading, cell differentiation and neurite outgrowth, increased proliferation of PC 12 cells, studies of effects of collagen IV on cell behaviour, cell adhesion assays, and serum-free or reduced serum culture.