MDx-Chex for BCID2 is a quality control for verifying the performance of the BIOFIRE® Blood Culture Identification 2 (BCID2) Panel for sepsis. MDx-Chex for BCID2 evaluates the entire analytical process of the assay, including cell lysis, DNA extraction, purification and removal of PCR inhibitors, as well as qPCR amplification, detection and analysis.

• Comprised of inactivated microorganisms in a matrix of blood cells and culture media components to simulate a patient sample
• Two BIOFIRE BCID2 pouches needed for complete coverage of all 43 targets,  which are contained in two vials
• Allows for direct use on the BIOFIRE Film Array Torch and 2.0 platforms
• Easy to use Pipette like a patient sample from a blood culture bottle
• No pooling of individual microorganisms needed
• Use 2 pouches vs. 6 pouches, as needed with some competitor controls
• Provides complete target coverage

MDx-Chex for BCID2 is a patient-like full process control designed to validate the entire analytical process of the BIOFIRE BCID2 Panel. The control kit contains 43 bacteria, yeasts and antimicrobial resistance gene targets packaged in two separate vials, one for Gram (-) bacteria and one for the Gram (+) bacteria and yeasts, covering targets tested on the BIOFIRE BCID2 Panel. The microorganisms are intact, inactivated and suspended in a matrix of stabilized red blood cells, white blood cells and blood culture media components, which is designed to challenge the lysis and purification processes just like a patient sample.

MDx-Chex for BCID2 is mixed and pipetted like a positive patient blood culture bottle specimen. Pooling of microorganisms and 'spike ins' of DNA are not needed, reducing the risk of cross-contamination, pipetting errors or other pre-analytical variables that may cause incorrect results.

A comprehensive, sample-to-result test requires a comprehensive control to validate the entire analytical process. MDx-Chex for BCID2 is such a control.