Collagen is the most abundant protein found in animals. During a healthy life span the insoluble, covalent, cross-linked collagen fibers retain their biophysical functions and shapes. The collagen fibers remain isolated from most of the biochemical activities of the cells.

• Dye-binding method
• It replaces the conventional hydroxyproline analysis. No more working with concentrated acids or alkalis
• The Sircol Insoluble Assay uses mild acid and temperature treatment for 2 to 3 hrs