The Ultra II Directional RNA Library Prep Kit for Illumina delivers significantly increased sensitivity and specificity from your RNA-seq experiments, from ever-decreasing amounts of input RNA. In conjunction with ribosomal RNA (rRNA) depletion or poly(A) enrichment, the kit enables the production of high quality libraries from 5 ng or 10 ng of Total RNA, respectively, up to 1 µg.

• Generate the highest yields of high quality libraries, with a broad range of input amounts
• Increase the complexity and transcript coverage of your libraries
• Optimize your time with streamlined workflows, reduced hands-on time, and automation compatibility
• Rely on robust performance, even with low quality RNA, including FFPE
• Enjoy the flexibility and reliability of the gold standard SPRIselect beads

The NEBNext Ultra II Directional RNA Library Prep Kit derives its directionality from the 'dUTP' method for strand-specificity, with proven superiority for this application. For convenience, this kit includes SPRISelect beads.