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L(+)-Histidine 98.5-101.5% (dried basis) USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
L(+)-Histidine 98.5-101.5% (dried basis) USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
Supplier:  AVANTOR PERFORMANCE MATERIAL LLC
Certificates
L(+)-Histidine 98.5-101.5% (dried basis) USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
Supplier:  AVANTOR PERFORMANCE MATERIAL LLC
Certificates

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Specification Test Results

  • USP - Assay (C H N 0 ) (dried basis):
    98.5 - 101.5%
  • USP - Identification:
    Passes Test
  • USP - Specific Rotation [A)25 AO (+):
    12.6 - 1.4.0°
  • USP - pH:
    7.0 - 8.5
  • USP - Loss on Orying at 105 °C:
    ≤0.2%
  • USP - Residue on Ignition:
    ≤0..4%
  • USP - Chloride (Cl):
    ≤0.05%
  • USP - Sulfate (S04):
    ≤0.03%
  • USP - Iron (Fe):
    ≤0.003%
  • USP - Related Compounds - Individual Impurities:
    ≤0.5%
  • USP - Related Compounds - Total Impurities:
    ≤2.0%
  • EP/BP - Assay (C H N 0 ) (dried basis):
    98.5 - 101.0%
  • EP/BP - Identification A:
    Passes Test
  • EP/BP - Identification B:
    Passes Test
  • EP/BP - Appearance of Solution:
    Passes Test
  • EP/BP - Specific Rotation [A)2°AO (+):
    11..4 - 12..4°
  • EP/BP-Ninhydrin-Positive Substances-Each:
    ≤0.2%
  • EP/BP-Ninhydrin-Positive Substances-Total Impurities:
    ≤0.5%
  • EP/BP - Chloride (Cl):
    ≤200 ppm
  • EP/BP - Sulfate (S04):
    ≤300 ppm
  • EP/BP - Ammonium (NH4):
    ≤0.02%
  • EP/BP - Iron (Fe):
    ≤10 ppm
  • EP/BP - Loss on Orying:
    ≤0.5%
  • EP/BP - Ash (sulfated):
    ≤0.1%
  • JP - Assay (C6H9N302) (dried basis):
    99.0 - 101.0%
  • JP - Ammonium (NH4):
    ≤0.02%
  • JP - Chloride (Cl):
    ≤0.021%
  • JP - Clarity and Color of Solution:
    Passes Test
  • JP - Iron (Fe):
    ≤10 ppm
  • JP - Identification:
    Passes Test
  • JP - Loss on Orying at 105 °C:
    ≤0.30%
  • JP- 0ptical Rotation [A)2°AO (+):
    11.8 - 12.8°
  • JP - Related Substances:
    Passes Test
  • JP - pH:
    7.0 - 8.5
  • JP - Residue on Ignition:
    ≤0.1%
  • JP - Sulfate (S04):
    ≤0.028%
  • ChP - Assay (dried basis):
    99.0 - 101.0%
  • ChP -Specific Rotation @ 20 °C (+):
    12.0 - 12.8°
  • ChP - Identification 1 (TLC):
    Passes Test
  • ChP - Identification 2 (IR):
    Passes Test
  • ChP - Acidity or alkalinity (pH):
    7.0 - 8.5
  • ChP - Transmittance of solution:
    ≥ 98.0%
  • ChP - Chlorides:
    ≤0.02%
  • ChP - Sulfates:
    ≤0.02%
  • ChP - Ammonium:
    ≤0.02%
  • ChP - 0ther amino acids (TLC)(<=0.5%, one spot only):
    Passes Test
  • ChP - Loss on drying @ 105 °C:
    ≤0.2%
  • ChP - Residue on ignition:
    ≤0.1%
  • ChP - Iron:
    ≤0.001%
  • ChP - Heavy metals:
    ≤0.001%
  • ChP - Arsenic:
    ≤0.0001%
  • ChP - Bacterial endotoxin, EU/g:
    ≤6.0

Specification Test Results

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