L(+)-Histidine 98.5-101.5% (dried basis) USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
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About this item
Synonyms: L-3-Imidazol-4-ylalanine, (S)-(+)-Histidine, (S)-2-Amino-3-(4-imidazolyl)propionic acid, H-His-OH, NSC 137773, L-Histidine
CAS Number:71-00-1
:
Formula:C₆H₉N₃O₂
MDL Number:MFCD00064315
Density:1.44 g/cm³ (20 °C)
Molecular Weight:155.16 g/mol
Melting Pt:287 °C
Merck Index:13,04741
:Management of Change (MOC) category = R
Storage Temperature:Ambient
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Specifications
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Specifications
Specification Test Results
- USP - Assay (C H N 0 ) (dried basis):98.5 - 101.5%
- USP - Identification:Passes Test
- USP - Specific Rotation [A)25 AO (+):12.6 - 1.4.0°
- USP - pH:7.0 - 8.5
- USP - Loss on Orying at 105 °C:≤0.2%
- USP - Residue on Ignition:≤0..4%
- USP - Chloride (Cl):≤0.05%
- USP - Sulfate (S04):≤0.03%
- USP - Iron (Fe):≤0.003%
- USP - Related Compounds - Individual Impurities:≤0.5%
- USP - Related Compounds - Total Impurities:≤2.0%
- EP/BP - Assay (C H N 0 ) (dried basis):98.5 - 101.0%
- EP/BP - Identification A:Passes Test
- EP/BP - Identification B:Passes Test
- EP/BP - Appearance of Solution:Passes Test
- EP/BP - Specific Rotation [A)2°AO (+):11..4 - 12..4°
- EP/BP-Ninhydrin-Positive Substances-Each:≤0.2%
- EP/BP-Ninhydrin-Positive Substances-Total Impurities:≤0.5%
- EP/BP - Chloride (Cl):≤200 ppm
- EP/BP - Sulfate (S04):≤300 ppm
- EP/BP - Ammonium (NH4):≤0.02%
- EP/BP - Iron (Fe):≤10 ppm
- EP/BP - Loss on Orying:≤0.5%
- EP/BP - Ash (sulfated):≤0.1%
- JP - Assay (C6H9N302) (dried basis):99.0 - 101.0%
- JP - Ammonium (NH4):≤0.02%
- JP - Chloride (Cl):≤0.021%
- JP - Clarity and Color of Solution:Passes Test
- JP - Iron (Fe):≤10 ppm
- JP - Identification:Passes Test
- JP - Loss on Orying at 105 °C:≤0.30%
- JP- 0ptical Rotation [A)2°AO (+):11.8 - 12.8°
- JP - Related Substances:Passes Test
- JP - pH:7.0 - 8.5
- JP - Residue on Ignition:≤0.1%
- JP - Sulfate (S04):≤0.028%
- ChP - Assay (dried basis):99.0 - 101.0%
- ChP -Specific Rotation @ 20 °C (+):12.0 - 12.8°
- ChP - Identification 1 (TLC):Passes Test
- ChP - Identification 2 (IR):Passes Test
- ChP - Acidity or alkalinity (pH):7.0 - 8.5
- ChP - Transmittance of solution:≥ 98.0%
- ChP - Chlorides:≤0.02%
- ChP - Sulfates:≤0.02%
- ChP - Ammonium:≤0.02%
- ChP - 0ther amino acids (TLC)(<=0.5%, one spot only):Passes Test
- ChP - Loss on drying @ 105 °C:≤0.2%
- ChP - Residue on ignition:≤0.1%
- ChP - Iron:≤0.001%
- ChP - Heavy metals:≤0.001%
- ChP - Arsenic:≤0.0001%
- ChP - Bacterial endotoxin, EU/g:≤6.0
Specification Test Results
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