Specifications

• Conjugation:
  Biotin
• Protein/Peptide Type:
  Recombinant
• Source:
  HEK293 cells
• Species:
  Cynomolgus monkey
  Rhesus monkey
• Tag sequence:
  His, Avitag™
• Storage Conditions:
  –20 °C
• Endotoxin Content:
  Less than 1.0 EU per μg by the LAL method.
• Biological Activity:
  Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag (SPR verified) (Cat. No. FCM-C82W3) captured on Biotin CAP-Series S Sensor Chip can bind Herceptin® with an affinity constant of 0.119 μM as determined in a SPR assay (Biacore T200) (QC tested). Loaded Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag (SPR verified)(Cat. No. FCM-C82W3) on SA Biosensor, can bind Cynomolgus Serum Albumin, His Tag(Cat. No. CSA-C52H4) with an affinity constant of 0.617 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
• Gene ID:
  Q8SPV9-1 (FCGRT) & Q8SPW0-1 (B2M)
• Protein Synonyms:
  FcRn|FCGRT & B2M
• Protein/Peptide Name:
  FcRn (FCGRT & B2M)
• Purity:
  >95% as determined by SDS-PAGE.
• Molecular Weight:
  34.1 kDa (FCGRT) & 11.6 kDa (B2M)
• Endotoxin Level:
  Low
• Formulation:
  Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
• Shipping Temperature:
  RT