The Monarch® gDNA Tissue Lysis Buffer is a component of the Monarch® Genomic DNA Purification Kit (NEB #T3010), which can be used to purify up to 30 µg genomic DNA from a variety of sample types.

The Tissue Lysis Buffer supplies intermediate lysis conditions that enable rapid digestion of the tissue pieces while simultaneously ensuring the genomic DNA fragment length is optimal for binding and elution.

The Monarch® gDNA Tissue Lysis Buffer is one of three lysis buffers available for purchase separately for additional convenience and to minimize waste.

Coupled with optimized Proteinase K digestion, the tissue lysis system facilitates above-average yields for common animal tissues , including tissues that prove difficult for many other commercial kits (e.g., brain and muscle).