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Specifications
- Description:Additive Screen Reagent
- Size:1 ml
- Environmentally Preferable:
- Cat. No.:MSPP-HR2138
- Supplier no.:HR2-138
Specifications
About this item
Manipulate sample-sample and sample-solvent interactions to improve crystals or alter sample solubility.
- Reagent of 18 classes
- Highly concentrated (10X) reagent formulation
- Tube or deep well block format and
- Contain 96 unique reagents and excipients
- Crystallization or sample solubility optimization
Additive screen is a library of reagents that can affect the solubility and crystallization of biological macromolecules, including both soluble and membrane proteins. These reagents can perturb and manipulate sample-sample and sample-solvent interactions, as well as perturb water structure which can alter and improve both the solubility and crystallization of a sample.
Additives can stabilize or engender conformity by specific interaction with the macromolecules. There are numerous reports of the use of additives to improve the quality and size of macromolecular crystals. Additive screen reagent classifications include multivalent, salt, amino acid, dissociating agent, linker, polyamine, osmolyte, chaotrope, co-factor, reducing agent, chelating agent, polymer, carbohydrate, non-detergent, amphiphile, detergent, non-volatile organic and volatile organic.