Mouse Recombinant IL13RA2/CD213A2 Protein (His & Fc Tag) (from HEK293 Cells)

About this item

A DNA sequence encoding the extracellular domain (Met 1-Lys 334) of mouse IL13Rα2 (NP_032382.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

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Specifications

Conjugation:
Unconjugated
Protein Function:
Immunotherapy
Protein/Peptide Type:
Recombinant
Source:
HEK293 cells
Species:
Mouse
Storage Conditions:
–20…–80 °C
Endotoxin Content:
<1.0 EU per μg of the protein as determined by the LAL method
Biological Activity:
1. Immobilized human IL13 at 20 μg/ml (100 μl/well) can bind mouse IL13RA2 with a linear range of 0.5-2 μg/ml.
2. Measured by its ability to inhibit IL13-dependent proliferation of TF1 human erythroleukemic cells. The ED50 for this effect is typically 5-30 ng/ml.
Gene ID:
NP_032382.1
Reconstitution Instructions:
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Carrier-Free:
Y
Animal-Free:
Y
Protein Synonyms:
CD213A2|IL-13R|CT19|IL13BP
Protein/Peptide Name:
IL13Ra2
Purity:
>85% as determined by SDS-PAGE.
Molecular Weight:
The recombinant mouse IL13Rα2/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 561 amino acids and has a predicted molecular mass of 64.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIL13Rα2/Fc monomer is approximately 75-80 kDa due to glycosylation.
Sequence:
Met1-Lys334
Shipping Temperature:
Ambient