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- Description:Oxysterol Derivatization MaxSpec® Kit
- Cat. No.:76266-344
- Contents:Kit contains: Girard's Reagent P, Girard's Reagent P-d5, Oxysterol Derivatization MaxSpec® Cholesterol Oxidase, and Oxysterol Derivatization MaxSpec® System Suitability Mixture
Derivatization Kit for the sensitive LC-MS analysis of oxysterols.
- Oxidation and derivatization kit for mass spec analysis of oxysterols
- Includes labeled and unlabeled derivatizing reagents that allow for a variety of sample workflows
- Can be used for quantitation or untargeted profiling methods
Cayman's Oxysterol Derivatization MaxSpec® Kit is designed for the sensitive detection and relative quantitation of oxysterols in biological samples. This is achieved through enzyme-assisted derivatization utilizing d0/d5 labeled Girard’s P reagent to give GP hydrazones. The instrumental response of the derivatized oxysterols is significantly improved due to the presence of a positively charged quaternary nitrogen group in the labeled and unlabeled GP hydrazones. Included in this kit are the essential reagents to derivatize oxysterols in mixtures for sensitive and comparative LC-MS analysis.