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Specifications
- Description:Glutathione HPLC Column, 1 column
- Cat. No.:102994-488
- Supplier no.:IC1800RP
Specifications
About this item
Glutathione HPLC assay kit column can be used for about 500 to 1000 samples.
- For use with glutathione HPLC assay kit
Most of the intracellular glutathione is reduced (approx. 90% in EDTA-blood), only 10% is oxidized (GSSG). The NADPH-dependent glutathione reductase maintains this steady state. Alterations in the glutathione status are involved in the pathogenesis of several diseases. In discussion are reperfusion damage, liver injury, cancer, diabetes mellitus, cataract, inflammatory diseases, chronic lymphatic edema and radiation damages. Altered glutathione concentrations might also be due to pollution, cigarette smoke, side effects of drugs and aging. In case of oxidative stress the amount of reduced glutathione is diminished. The relation of reduced to oxidized glutathione gives information about the redox and detoxification status of cells and tissue.