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Specifications
- Host:
- Primary antibody reactivity:
- Description:Lipoxin A4 ELISA Kit
- Size:1 kit
- Environmentally Preferable:
- Cat. No.:102994-744
- Supplier no.:LA439-K01
Specifications
About this item
Lipoxin A4 ELISA is to detect Lipoxin A4 in biological fluids by a microplate enzyme immuno.
- Dynamic Range: 0.02 - 2.0 ng/mL
- Sensitivity: 0.02 ng/mL
- Incubation: 2 hours
Lipoxin A4 (LXA4) is a biologically active lipoxygenase interaction product derived from arachidonic acid. Arachidonic acid is first oxygenated by 15-lipoxygenase to form 15-HETE which is converted by 5-lipoxygenase and epoxide hydrase to generate LXA4. LXA4 stimulates leukocyte chemotaxis without aggregation and inhibits natural killer cell cytotoxicity. It also provokes contraction of parenchymal strips and stimulates microvascular changes. Recent findings indicate that LXA4 inhibits leukocyte-dependent inflammation. Determination of LXA4 level may provide new understanding of the role of LXA4 in basic cellular reactions and in pathophysiology of inflammation and other disease processes.