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- Target protein:ADMA
- Description:ADMA (Asymmetric Dimethylarginine) / Arginine ELISA
- Size:1 kit
- Cat. No.:102993-870
- Supplier no.:AAP31-K02
ADMA / Arginine ELISA detects Endogenous ADMA and L-Arginine in EDTA-Plasma, for research use only.
- Dynamic Range: ADMA: 0.1 - 5.0 µmol/L, Arginine: 6 - 600 µmol/L
- Sensitivity: ADMA: 0.01 µmol/L, Arginine: 3.0 µmol/L
- Incubation: Overnight
Importantly, high ADMA levels and low L-arginine/ADMA ratio were both independent predictors of death in the community-based Framingham Offspring Study. As ADMA competes with L-arginine for binding to NO synthase, many scientists suggest that the L-arginine/ADMA ratio is a better index of NOS substrate availability and, thus, functional integrity of the NOS pathway, than L-arginine levels alone.