Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Primary antibody reactivity:Mouse
- Target protein:IGFBP-3
- Description:Mouse-/ Rat-IGFBP-3 ELISA
- Size:1 kit
- Cat. No.:102994-270
- Supplier no.:E031
Specifications
About this item
Mouse/Rat IGFBP-3 ELISA measures IGFBP-3 in mouse and rat serum, plasma and in cell culture medium.
- Dynamic Range: 0.78 - 5 ng/mL
- Sensitivity: 0.018 ng/mL
- Incubation: 2.5 hours
IGFBP-3 is the most abundant IGFBP in circulation and therefore of special relevance in regulation of IGF effects. This is reflected by the indicative value of serum IGFBP-3 concentration in diagnostics of growth disturbances. Regulation is effected e.g. through nourishing situation; Different diets for example affect the IGFBP-3 concentration (Bielohuby et al, 2010). IGFBP-3 has also been shown to be able to induce apoptosis, promote tumor growth and inhibit cellular migration and metastasis dependent on tissue and tumor stage.