Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Size:500 Assays
- Cat. No.:103010-166
- Storage temperature:–20 °C
- Includes:The assays can be performed in a convenient 96-well or 384-well microplate format, kit includes essential components and detailed protocol and references
- Supplier no.:AS-71137
Specifications
About this item
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components
The SensoLyte® 490 MMP-12 Assay Kit is a complete assay system designed to continuously analyze MMP-12 activity or to screen for MMP-12 inhibitors by using a fluorogenic MMP-12 substrate. The assays are performed in a convenient 96-well or 384-well microplate format. It provides speed, convenience and accuracy in analyzing MMP-12 and in screening MMP-12 inhibitors.
MMP-12 (macrophage elastase) is implicated in the pathology of many diseases such as emphysema, aortic lesions and cancer. It has recently been shown to play a role in the pathogenesis of rheumatoid arthritis.