The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.

Type: Primary
Antigen: CD117 (c-Kit) (ACK2)
Clonality: Monoclonal
Clone: ACK2
Conjugation: PE (Phycoerythrin)-Cy7®
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse