Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/us/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Conjugation:Unconjugated
- Size:5 mg
- Storage Conditions:–20 °C
- Protein Synonyms:Myelin basic protein substrate|Mitogen-activated protein kinase substrate
- Protein/Peptide Name:MBP MAPK Substrate
- Purity:95%
- Molecular Weight:967.1 Da
- Sequence:APRTPGGRR
- Cat. No.:102996-874
- Supplier no.:AS-27168
Specifications
About this item
The sequence APRTPGGRR contains a native sequence derived from bovine myelin basic protein amino acids 95-98 (PRTP). The rest of the sequence is not derived from a native sequence, but is a synthetic construct. This substrate is specific for MAP kinases: p44MAPK [extracellular signal-regulated kinase 1 (ERK1)] and p42MAPK (ERK2). It contains the consensus sequence Pro-X-(Ser/Thr)-Pro that is recognized by MAP kinase. This peptide is the most efficient substrate for phosphorylation reaction by ERK. The substrate is phosphorylated by kinases on threonine 97 and can also be phosphorylated by MAPK p38.
Sequence:APRTPGGRR
MW:967.1 Da
% peak area by HPLC:95
Storage condition:-20° C