Zeta Plus™ Encapsulated System Scale-Up Filter Capsules with LA Media as single-use depth filtration capsules for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required. The encapsulated lenticular design and vertical flow path help provide consistent performance between formats.

• High purity pre-extracted filter-aid and cellulose provides low extractable levels, especially aluminum
• FDA Drug Master File and USP Class VI Biological Reactivity Tests eases validation and regulatory submissions by providing vital documentation and traceability
• Self-contained, single-use capsules are available in three convenient sizes for scale-up and benchtop studies

Zeta Plus™ Encapsulated System Scale-Up Filter Capsules with LA Media is a family of advanced depth filters that are low in extractables and are designed to provide superior clarification of bioprocess, biological, and pharmaceutical fluids.

These capsules are ideal for laboratory and scale-up studies. In addition to mechanical filtration, the Zeta Plus LA Series Filter Media exhibits a positive electrokinetic charge that enhances filtration efficiency by removing sub-micron particles through adsorption-the adhesion of particles to the charged filter surface. Zeta Plus LA Series Filter Media provides low levels of inorganic extractables, especially aluminum, making it a premium grade filter media ideal for parenteral, blood fractionation, bioprocess and infant food/formula applications. The Zeta Plus LA Series products are manufactured to stringent quality controls to provide reproducible product performance from filter to filter, and lot to lot. When used as a pre-filter, the high contaminant holding capacity of Zeta Plus LA Series Filter Media can prolong the life of the final stage filter.

Zeta Plus LA Series Filter Media is manufactured to controls described in our Drug Master File on record with the FDA. Certificates of Quality are included with the packaging of every filter. These filters meet the requirements of USP Class VI Biological Reactivity Tests and meet the strict requirements specified in the Drug Master File, including product control and traceability.

Encapsulating High Performance.

Applications include Parenterals, Dialysates, Blood Fractionation, Bioprocess Fluids and Infant Formula and Foods.
We utilize the lenticular filter design and vertical flow path on our Zeta Plus™ Encapsulated System Scale-Up Filter Capsules that have been proven effective for depth filtration systems. A total of four single-use scale-up capsules are available for media grade selection and filter sizing. The BC25 capsule with 25 cm2 filter media is ideal for media grade screening. The Scale-Up Capsule filters with 170, 340 and 1020 cm² media are designed for intermediate scale studies and low volume production filtration. Combined with the larger production scale capsules, the Zeta Plus Encapsulated System offers a completely single-use solution to process from 100 ml to 25000 L of liquid.