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Specifications
- Conjugation:Unconjugated
- Species:Human
- Size:1 mg
- Storage Conditions:–20 °C
- Protein Synonyms:Ang Peptide chymosin substrate|Ang II|Ang II substrate|Chymosin substrate Peptide|Angiotensin II substrate|human Ang II substrate
- Protein/Peptide Name:Angiotensin II Substrate
- Purity:95%
- Molecular Weight:1126.2 Da
- Sequence:DRV-pY-IHPF
- Cat. No.:103003-754
- Supplier no.:AS-24520
Specifications
About this item
This is a tyrosine phosphorylated angiotensin II peptide with a substrate sequence specificity for chymase to act. This is an octapeptide hormone that is formed as a result of the action of human heart chymase, a chymotrypsin-like serine protease on the Phe-His bond of Angiotensin I. The ideal susbtrate for human heart chymase should contain this peptide sequence, and has been demonstrated that the Pro-Phe sequence in P2-P1 positions of peptide substrates is highly favored by leukocyte chymotrypsin-like proteinases such as chymases and cathepsin G.
Sequence: DRV-pY-IHPF
MW: 1126.2 Da
% Peak area by HPLC: 95
Storage condition: -20°C