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- Antibody Type:Primary
- Antigen Name:Cytokeratin 5/6
- Antigen Symbol:CK5/CK6
- Clonality:Monoclonal
- Clone:D5/16 B4
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Size:7 mL
- Form:Liquid
- Storage Temperature:+4 °C
- Purification:Purified by precipitation
- Cat. No.:75815-484
- Supplier no.:60-0016-7
For In Vitro Diagnostic Use.
This product is used to qualitatively detect Cytokeratin 5/6 in normal and neoplastic formalin fixed paraffin embedded (FFPE) tissue sections in immunohistochemical (IHC) detection methodology. Interpretation must be made within the context of the patient’s clinical history and other diagnostic test by a qualified pathologist.
This antibody labels Cytokeratin 5 and 6, and is useful for the differentiation between low differentiated squamous cell carcinoma and adenocarcinoma, and between epithelial mesothelioma and metastatic carcinoma in the pleura when using together with a panel of other antibodies (e.g. Calretinin, TTF-1). Anti-Cytokeratin 5/6 has also been found useful in the differential diagnosis of atypical proliferations of the breast.
This antibody is purified immunoglobulin diluted in 10 mM phosphate buffered saline (PBS), pH 7.2 containing 1% bovine serum albumin (BSA) and 0.09% sodium azide (NaN3) as antimicrobial agent.
For professional users.
Proper handling of this product as with any product derived from biological sources according to local and applicable regulations.
Sodium azide is a toxic chemical. The concentration in this product is not classified as hazardous. However, the build-ups of NaN3 may react with lead and copper plumbing to form highly explosive metal azides. Flush the disposed reagent with large volume of water to prevent azide build-up.
60-0016-7: Ready-To-Use
61-0016; 61-0016-2: Dilute 1:50 to 1:100 before use when using Acu-StainTM detection system. Optimum dilution factor may vary depending on the specimen and preparation process and should be determined by each individual investigator.
Incubate this antibody with tissue section for 30-60 minutes at room temperature. Follow the instructions from the selected detection system.
Positive Control: Mesothelioma, prostate
Antigen Retrieval: HIER, Tris pH 9
Staining Pattern: Cytoplasm
Type: Primary
Antigen: CK5/CK6
Clonality: Monoclonal
Clone: D5/16 B4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human