YMC-Triart C18, 5 µm semi-preparative and preparative columns are packed with a novel, organic/inorganic hybrid silica particles derivatized with C18. Triart C18 columns feature chemical stability and mechanical strength, operation over a wide pH range of 1 to 12, high loading capacity, narrow particle and pore size distributions, and the ability to operate in 100% aqueous environments. Triart C18 5 µm semi-preparative and preparative columns are available in many column geometries.

• Chemical stability of YMC-Triart C18, 5 µm combines with inherent mechanical durability of particles to contribute to long column lifetime
• Available in columns packed with 5 µm particles, operating over a wide pH range of 1 to 12; this enables the manipulation of retention and preparative loading
• Semi-preparative and preparative columns for HPLC feature high loading capacity
• Available in column diameters of 6, 10, 20, 30, 50 and 100 mm stainless steel hardware in many column lengths
• Semi-preparative and preparative columns for HPLC feature legendary YMC column-to-column and lot-to-lot reproducibility
• Unlike other hybrid materials, Triart C18, 5 µm columns exhibit a balanced hydrophobicity; it is more retentive than other hybrid materials, potentially simplifying the separation of "difficult" peaks
• May be operated in 100% aqueous mobile phases

YMC-Triart C18, 5 µm is a novel organic/inorganic hybrid silica particle derivatized with C18 (L1 USP designation).

The core material for all of the YMC-Triart products, the particle, is inspired by YMC’s flow chemistry technology. Inherent in YMC’s process is a high level of temperature and particle formation control. As a result, Triart particles are consistent, reproducible, and scalable across many particle sizes with narrow particle and pore size distributions. The hybrid Triart 18 particles produce a material that is highly resilient and robust when used at extreme pH and elevated temperature. In addition, these particles are very stable under mechanical stress, such as high pressure. YMC-Triart C18, 5 µm can be used at temperatures up to 70 °C at pH 1 to 7, and 50 °C from pH 7 to 12. This allows the chromatographer to use temperature and pH as tools to optimize suitable separation and loading conditions, and be less worried about the limitations of stationary phase ruggedness. The columns may be cleaned with base and feature extremely low levels of leachables, well below that of traditional silica C18 derivatized stationary phases.

The chemistry of the C18 is enhanced by an end capping process that eliminates the secondary interactions that contribute to poor peak shape, and is ideal for analysis of all types of compounds. Triart C18 is an ideal first-choice method development column.