Cleanert® ODS C18 columns are packed with octadecylsilane bonded silica sorbents.

Cleanert® ODS C18-N is a type of C18 sorbent bonded to silica without end-capping modification, providing extra silanol residuals around the 'root' of alkyl chain on silica surface. The extra silanol silica of the sorbent provide additional polar interactions associated with surface silanol groups which enhance the retention of basic compounds.

The sorbent is double endcapped and has a high bonding density (%C >17). These products can be used for desalting biomolecules, such as proteins and DNAs.