About this item
Nuclear NMNAT isoform
- UniProt link Q9HAN9: NMNAT1 (human)
Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. It can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
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Specifications
- Conjugation:Unconjugated
- Source:E. coli
- Species:Human
- Storage Conditions:−20 °C
- Form:Liquid
- Shipping Conditions:–20 °C, blue Ice
- Enzyme Name:NMNAT1
- Enzyme Activity:>5U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1µmol of NAD+ per min.
- Purity:95%
- Molecular Weight:~33.3 kDa (monomer)
- Concentration:~1 mg/ml
- Formulation:In 50 mM sodium phosphate, pH 8.0, containing 300 mM sodium chloride, 2 mM DTT and 10% glycerol.