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Specifications
- Antibody Type:Primary
- Antigen Symbol:CD275
- Clonality:Monoclonal
- Clone:ANC4E3
- Conjugation:Unconjugated
- ELISA:Yes
- Isotype:IgG1 kappa
- Reactivity:Human
- Size:100 µg
- Form:liquid
- Antigen Synonyms:ICOS Ligand|B7-H2|B7RP-1|B7-like Protein Gl50
- Storage Temperature:+4°C
- Shipping Temperature:-20° C
- Immunogen:Human Raji cells, recombinant human CD275-muIg.
- Cat. No.:102512-694
- Supplier no.:ANC263020
Specifications
About this item
The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Type: Primary
Antigen: CD275
Clonality: Monoclonal
Clone: ANC4E3
Conjugation: Unconjugated
Epitope:
Host:
Isotype: Mouse IgG1kappa
Reactivity: Human