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Specifications
- Antibody Type:Primary
- Antigen Symbol:CD8A
- Clonality:Monoclonal
- Clone:53-6
- ELISA:Yes
- Flow Cytometry:Yes
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Size:120 tests
- Form:liquid
- Storage Temperature:+4°C
- Shipping Temperature:-20° C
- Immunogen:murine thymocytes/splenocytes.
- Cat. No.:102512-672
- Supplier no.:ANC260040
Specifications
About this item
CD8 identifies cytotoxic/suppressor T cells that interact with MHC Class I bearing targets. CD8 is thought to play a role in the process of T cell mediated killing. CD8-alpha chains binds to Class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Type: Primary
Antigen: CD8A
Clonality: Monoclonal
Clone: 53-6
Conjugation: FITC
Epitope:
Host:
Isotype: Rat IgG2akappa
Reactivity: Mouse