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United States
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Anti-Bcl-xL Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 7B2.5]
Catalog # 100242-228
Anti-Bcl-xL Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 7B2.5]
Catalog # 100242-228
Supplier Number:  10030-02
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Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Bcl-xL
  • Antigen Symbol:
    Bcl-xL
  • Clonality:
    Monoclonal
  • Clone:
    7B2.5
  • Conjugation:
    FITC (Fluorescein Isothiocyanate)
  • Flow Cytometry:
    Yes
  • Host:
    Mouse
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG3
  • Reactivity:
    Rhesus monkey,
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    0.1 mg
  • Environmentally Preferable:
  • Form:
    Liquid
  • Gene ID:
    598
  • Antigen Synonyms:
    BCL2L1|Apoptosis regulator Bcl-X|Bcl-2-like 1 protein
  • Storage Buffer:
    Supplied in PBS/NaN3
  • Storage Temperature:
    2-8°C
  • Concentration:
    0.1 mg/mL
  • Shipping Temperature:
    Ambient Temperature
  • Immunogen:
    Recombinant human Bcl-xS
  • Cat. No.:
    100242-228
  • Supplier no.:
    10030-02

Specifications

About this item

Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

Type: Primary
Antigen: Bcl-xL
Clonality: Monoclonal
Clone: 7B2.5
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse, Rat, Rhesus