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Specifications
- Antibody Type:Primary
- Antigen Name:Bcl-xL
- Antigen Symbol:Bcl-xL
- Clonality:Monoclonal
- Clone:7B2.5
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow Cytometry:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG3
- Reactivity:Rhesus monkey,Human,Rat,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Environmentally Preferable:
- Form:Liquid
- Gene ID:598
- Antigen Synonyms:BCL2L1|Apoptosis regulator Bcl-X|Bcl-2-like 1 protein
- Storage Buffer:Supplied in PBS/NaN3
- Storage Temperature:2-8°C
- Concentration:0.1 mg/mL
- Shipping Temperature:Ambient Temperature
- Immunogen:Recombinant human Bcl-xS
- Cat. No.:100242-228
- Supplier no.:10030-02
Specifications
About this item
Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.
Type: Primary
Antigen: Bcl-xL
Clonality: Monoclonal
Clone: 7B2.5
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human, Mouse, Rat, Rhesus