About this item
The αβ TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with γδ TCR-bearing cells. Plate-bound or soluble H57-597 activates αβ TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete αβ TCR-bearing cells to near completion and prevent graft rejection.
Type: Primary
Antigen: TCRbeta
Clonality: Monoclonal
Clone: H57-597
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse
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Specifications
- Catalog No:
- 100243-760
- 100243-762
- Antigen Symbol:
- TCRbeta
- TCRbeta
- Antigen Name:
- TCR beta
- TCR beta
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- FITC (Fluorescein Isothiocyanate)
- FITC (Fluorescein Isothiocyanate)
- Clone:
- H57-597
- H57-597
- Reactivity:
- Mouse
- Mouse
- Host:
- Hamster
- Hamster
- Gene ID:
- 21577
- 21577
- Isotype:
- IgG
- IgG
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Flow Cytometry:
- Yes
- Yes
- Immunogen:
- TCR affinity purified from mouse T-cell hybridoma DO-11.10
- TCR affinity purified from mouse T-cell hybridoma DO-11.10
- Form:
- Liquid
- Liquid
- Concentration:
- 0.5 mg/mL
- 0.1 mg/mL
- Storage Buffer:
- Supplied in PBS/NaN3
- Supplied in PBS/NaN3
- Storage Temperature:
- 2-8°C
- 2-8°C
- Shipping Temperature:
- Ambient Temperature
- Ambient Temperature