Anti-TCRbeta Hamster Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: H57-597]

About this item

The αβ TCR is expressed on T lymphocytes of all mouse strains tested. The H57-597 monoclonal antibody does not react with γδ TCR-bearing cells. Plate-bound or soluble H57-597 activates αβ TCR-bearing T cells. In vitro and in vivo, H57-597 can induce immature thymocytes to undergo apoptosis. In vivo administration of H57-597 has been shown to deplete αβ TCR-bearing cells to near completion and prevent graft rejection.

Type: Primary
Antigen: TCRbeta
Clonality: Monoclonal
Clone: H57-597
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse

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