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- Antibody Type:Primary
- Antigen Name:CD28
- Antigen Symbol:CD28
- Clonality:Monoclonal
- Clone:PV-1
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Hamster
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Mouse
- Size:0.5 mg
- Form:Liquid
- Gene ID:12487
- Antigen Synonyms:Tp44|T44
- Storage Buffer:Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
- Storage Temperature:2-8°C
- Concentration:0.5 mg/mL
- Shipping Temperature:Ambient Temperature
- Immunogen:C57BL/6N mouse T cell lymphoma EL4 cell line
- Tested Applications:Costim, Stim
- Cat. No.:100243-386
- Supplier no.:1615-01
CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.
Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: PV-1
Conjugation: Unconjugated
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse