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Specifications
- Antibody Type:Primary
- Antigen Name:CD11b
- Antigen Symbol:CD11b
- Clonality:Monoclonal
- Clone:3A33
- Conjugation:RPE (R-Phycoerythrin)/Cy7®
- Flow Cytometry:Yes
- Host:Rat
- Isotype:IgG2a
- Reactivity:Mouse
- Size:0.1 mg
- Form:Liquid
- Gene ID:16409
- Antigen Synonyms:C3biR|Mo1|Integrin αM|CR3|Mac-1|Mac-1α
- Storage Buffer:Supplied in PBS/NaN3 and a stabilizing agent
- Storage Temperature:2-8°C
- Concentration:0.1 mg/mL
- Shipping Temperature:Ambient Temperature
- Immunogen:Peritoneal macrophages from B6D2 hybrid mice
- Cat. No.:100243-224
- Supplier no.:1560-17
Specifications
About this item
CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
Type: Primary
Antigen: CD11b
Clonality: Monoclonal
Clone: 3A33
Conjugation: RPE (R-Phycoerythrin)/Cy7®
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse