Imject™ Mariculture KLH (mcKLH) is a purified keyhole limpet haemocyanin carrier protein that enables simple preparation of highly effective immunogens with peptide antigens.

• High-yield conjugation with each molecule of KLH contains hundreds of primary amines available for coupling haptens via EDC or NHS ester crosslinkers
• Validated quality with purified and stabilized mariculture KLH maintains solubility in aqueous solutions
• Sustainable source with KLH that is harvested from select populations of the mollusc that are grown in mariculture
• Highly immunogenic as KLH has a high molecular mass that elicits a stronger immune response

Mariculture KLH is purified and lyophilized in buffers that optimize its stability and solubility for hapten conjugation

Preparations in phosphate buffer (PBS) are ready for hapten-carrier conjugation via amine-reactive NHS-ester or glutaraldehyde crosslinking. Preparations in MES buffer are optimized for peptide-carrier conjugation via the carboxyl-reactive carbodiimide crosslinker called EDC (or EDAC).

The large, complex protein contains hundreds of sites per molecule for effective conjugation of peptides and other antigens using amine-reactive or carboxyl-reactive crosslinkers.