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Specifications
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:100 µg
- Gene ID:7032
- Protein Synonyms:SP|SML1|TFF2|Spasmolytic polypeptide|Spasmolysin
- Protein/Peptide Name:TFF2
- Molecular Weight:12 kDa
- Sequence:MKHHHHHHAS EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
- Cat. No.:102552-834
- Supplier no.:RD172159100
Specifications
About this item
Trefoil factor 2 (TFF2) (PSP – pancreatic spasmolytic polypeptide) is a small secreted protein with a molecular weight of 12 kDa. It belongs to the TFF protein family that is characterized by a clover leaf–like disulphide structure named the TFF domain, which is created by 6 cysteines forming three intramolecular bonds. TFF2 contains two trefoil domains and has a very compact structure which may account for its extremely high resistance against the harsh environment in the gastrointestinal tract. The most abundant expression of TFFs is found in GI tract (especially in stomach, colon and pancreas), where they are co-localised with mucins. TFF2 is usually co-localised with MUC6 and probably mediates mucin cross-linking and stabilization of the mucin layer as do the other members of the TFF family.
Sequence: MKHHHHHHAS EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Other names: Spasmolytic polypeptide, SP, Spasmolysin, TFF2, SML1