Human Recombinant Myelin P0-like 1 (from Cells)
Catalog # 75788-708
Supplier: Prosci
CAS Number:
Specifications
- Protein/Peptide Type:Recombinant
- Source:Cells
- Species:Human
- Size:0.05 mg
- Tag sequence:C-6 His tag
- Storage Conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein Synonyms:transcript variant 1|isoform CRA_b|highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1)|cDNA FLJ78597|FLJ96614|Homo sapiens myelin protein zero-like 1 (MPZL1)|Mrna|Myelin protein zero-like 1|MPZL1|cDNA|mRNA
- Protein/Peptide Name:Myelin P0-like 1
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular Weight:15.2 kD
- Sequence:Ser36-Val162
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:Bioassay
- Cat. No.:75788-708
- Supplier no.:92-390
Specifications
About this item
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.