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Human Recombinant BPI (from Cells)
Human Recombinant BPI (from Cells)
Catalog # 75790-336
Supplier:  Prosci
CAS Number:  
Human Recombinant BPI (from Cells)
Catalog # 75790-336
Supplier:  Prosci
Supplier Number:  91-842
CAS Number:  

Specifications

  • Protein/Peptide Type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage Conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein Synonyms:
    BPI|Bactericidal permeability-increasing protein|CAP57
  • Protein/Peptide Name:
    BPI
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    52.5 kD
  • Sequence:
    Val32-Lys487
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    Bioassay
  • Cat. No.:
    75790-336
  • Supplier no.:
    91-842

Specifications

About this item

Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.