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Human Recombinant Carboxypeptidase B (from Cells)
Human Recombinant Carboxypeptidase B (from Cells)
Catalog # 75789-498
Supplier:  Prosci
CAS Number:  
Human Recombinant Carboxypeptidase B (from Cells)
Catalog # 75789-498
Supplier:  Prosci
Supplier Number:  91-411
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage Conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme Name:
    Carboxypeptidase B
  • Enzyme Synonyms:
    Carboxypeptidase B, Pancreas-Specific Protein, PASP, CPB1, CPB, PCPB
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    46.94 kD
  • Sequence:
    His16-Tyr417 FUSION TAG: C-6 H
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    For Biological Assays
  • Cat. No.:
    75789-498
  • Supplier no.:
    91-411

Specifications

About this item

Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.