Human Recombinant PPIase (from E. coli)
Catalog # 75789-218
Supplier: Prosci
CAS Number:
Specifications
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Tag sequence:N-6 His tag
- Storage Conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Enzyme Name:PPIase
- Enzyme Synonyms:Peptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular Weight:20.4 kD
- Sequence:Met1-Gly166
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:Bioassay
- Cat. No.:75789-218
- Supplier no.:91-271
Specifications
About this item
Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family
This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag
PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.