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Human Recombinant PPIase (from E. coli)
Human Recombinant PPIase (from E. coli)
Catalog # 75789-218
Supplier:  Prosci
CAS Number:  
Human Recombinant PPIase (from E. coli)
Catalog # 75789-218
Supplier:  Prosci
Supplier Number:  91-271
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    N-6 His tag
  • Storage Conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme Name:
    PPIase
  • Enzyme Synonyms:
    Peptidyl-Prolyl Cis-Trans Isomerase-Like 1, PPIase, Rotamase PPIL1, PPIL1, CYPL1
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    20.4 kD
  • Sequence:
    Met1-Gly166
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    Bioassay
  • Cat. No.:
    75789-218
  • Supplier no.:
    91-271

Specifications

About this item

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: N-6 His tag

PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.