Human Recombinant UBE2S (from E. coli)
Catalog # 75789-214
Supplier: Prosci
CAS Number:
Specifications
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.05 mg
- Tag sequence:N-GST tag
- Storage Conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Endotoxin Content:<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
- Protein Synonyms:Ubiquitin-Conjugating Enzyme E2-24 kDa|E2-EPF|Ubiquitin-Conjugating Enzyme E2 S|E2EPF|UBE2S|Ubiquitin-Conjugating Enzyme E2-EPF5|Ubiquitin Carrier Protein S|Ubiquitin-Protein Ligase S
- Protein/Peptide Name:UBE2S
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular Weight:50.13 kD
- Sequence:Met1-Leu222
- Formulation:Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested Applications:Bioassay
- Cat. No.:75789-214
- Supplier no.:91-269
Specifications
About this item
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
- Fusion-Tag: N-GST tag
This recombinant protein can be used for biological assays. For research use only.