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Human Recombinant Inositol Monophosphatase 1 (from E. coli)
Human Recombinant Inositol Monophosphatase 1 (from E. coli)
Catalog # 75789-144
Supplier:  Prosci
CAS Number:  
Human Recombinant Inositol Monophosphatase 1 (from E. coli)
Catalog # 75789-144
Supplier:  Prosci
Supplier Number:  91-214
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    N-6 His tag
  • Storage Conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin Content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme Name:
    Inositol Monophosphatase 1
  • Enzyme Synonyms:
    Inositol Monophosphatase 1, IMP 1, IMPase 1, Inositol-1(or 4)-Monophosphatase 1, Lithium-Sensitive Myo-Inositol Monophosphatase A1, IMPA1, IMPA, IIMPase 2
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular Weight:
    32.3 kD
  • Sequence:
    Met1-Asp277
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested Applications:
    For Biological assays
  • Cat. No.:
    75789-144
  • Supplier no.:
    91-214

Specifications

About this item

Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: N-6 His tag

IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.