CellExp™ Human Recombinant HAVCR1 (from HEK293 cells)

>9% pure active human cell expressed human recombinant HAVCR1/KIM1/TIM1

Hepatitis A virus cellular receptor 1 also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.

Protein/Peptide Type:
Recombinant
Source:
HEK293 cells
Species:
Human
Endotoxin Content:
<1 EU/μg by LAL method
Reconstitution Instructions:
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Protein Synonyms:
TIM1|TIM-1|KIM-1|HAVCR|Hepatitis A virus cellular receptor 1|HAVCR-1|KIM1
Protein/Peptide Name:
HAVCR1
Purity:
>90%
Molecular Weight:
31.3 kDa
Formulation:
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.