Anti-TCF3 Rabbit Polyclonal Antibody
Catalog # 10813-814
Supplier: Prosci
Specifications
- Antibody Type:Primary
- Antigen Name:transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- Antigen Symbol:TCF3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Size:0.1 mg
- Form:Liquid
- Gene ID:P15923
- Antigen Synonyms:TCF3
- Modification:Thr 355
- Storage Buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular Weight:67 kDa
- Storage Temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:E2A (phospho Thr355) antibody was raised against a peptide sequence around phosphorylation site of threonine 355 (P-S-T (p)-P-V) derived from Human E2A .
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. No.:10813-814
- Supplier no.:79-908
Specifications
About this item
E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Type: Primary
Antigen: TCF3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat