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Anti-TCF3 Rabbit Polyclonal Antibody
Anti-TCF3 Rabbit Polyclonal Antibody
Catalog # 10813-814
Supplier:  Prosci
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Anti-TCF3 Rabbit Polyclonal Antibody
Catalog # 10813-814
Supplier:  Prosci
Supplier Number:  79-908

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
  • Antigen Symbol:
    TCF3
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Size:
    0.1 mg
  • Form:
    Liquid
  • Gene ID:
    P15923
  • Antigen Synonyms:
    TCF3
  • Modification:
    Thr 355
  • Storage Buffer:
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Molecular Weight:
    67 kDa
  • Storage Temperature:
    Store antibody at –20 °C for up to one year.
  • Concentration:
    1 mg/mL
  • Shipping Temperature:
    4 °C
  • Immunogen:
    E2A (phospho Thr355) antibody was raised against a peptide sequence around phosphorylation site of threonine 355 (P-S-T (p)-P-V) derived from Human E2A .
  • Purification:
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Cat. No.:
    10813-814
  • Supplier no.:
    79-908

Specifications

About this item

E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.

Type: Primary
Antigen: TCF3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat