>97% Pure active Recombinant Human IGF-I, R³, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue.

The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.

IGF-I (insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-I is a N-terminus modified IGF-I with a Long R3 chain, which shows higher potency than regular human IGF-I in bioactivity assay. The recombinant IGF-I Long R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.