Pierce™ TMT10plex™ Isobaric Mass Tag Labelling Kit and Reagent Sets, Thermo Scientific

: Invitrogen

Pierce™ TMT10plex™ Isobaric Mass Tag Labelling Kit and Reagent Sets, Thermo Scientific

: Invitrogen

TMT10plex™ Isobaric Mass Tag Labeling Reagents Sets enable multiplexed protein identification and quantitative analysis by tandem mass spectrometry (MS).

Increased sample multiplexing for relative quantitation
Increased sample throughput
Fewer missing quantitative channels among samples

Each mass-tagging reagent within a set has the same nominal mass (ie

The TMT10plex™ Label Reagents share an identical structure with Thermo Scientific™ TMTzero™ and TMTsixplex™ Reagents but contain different numbers and combinations of ¹³C and ¹⁵N isotopes in the mass reporter. The different isotopes result in a 10plex set of tags that have monoisotopic mass differences in the reporter that can be detected using high resolution mass spectrometry.

isobaric) and chemical structure composed of an amine-reactive NHS-ester group, a spacer arm and a mass reporter. The reagent set can be used to label up to ten different peptide samples prepared from cells or tissues. For each sample, a unique reporter mass (ie. TMT10 126-131Da) in the low mass region of the MS/MS spectrum is used to measure relative protein expression levels during peptide fragmentation.

: Includes reagents sufficient for: One 10-plex (1 x 10-way) experiment, Label reagents: TMT10-126, 1 x 0.8 mg, TMT10-127N, 1 x 0.8 mg, TMT10-127C, 1 x 0.8 mg, TMT10-128N, 1 x 0.8 mg, TMT10-128C, 1 x 0.8 mg, TMT10-129N, 1 x 0.8 mg, TMT10-129C, 1 x 0.8 mg, TMT10-130N, 1 x 0.8 mg, TMT10-130C, 1 x 0.8 mg and TMT10-131, 1 x 0.8 mg.

: For Research Use Only. Not for use in diagnostic procedures.

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