Human Recombinant Flt3-Ligand (from E. coli)

About this item

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.

Animal-free

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
Store at –20 °C prior to reconstitution.
Endotoxin Content:
>0.1 ng/μg
Biological Activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
2322 P49771
Reconstitution Instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Animal-Free:
Y
Protein Synonyms:
Flt3L|Fms-related tyrosine kinase 3 ligand
Protein/Peptide Name:
Flt3-Ligand
Purity:
0.98
Molecular Weight:
17.6 kDa
Sequence:
TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Endotoxin Level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping Temperature:
Ambient