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Mouse Recombinant Noggin (from E. coli)

Supplier:   Peprotech
Mouse Recombinant Noggin (from <i>E. coli</i>)
Supplier:  Peprotech
Certificates

4 Options Available Below

  • Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
  • Return Policy
Product Details & Documents

Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-β family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action was critical for proper formation of the head and other dorsal structures. Consequently, noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of noggin in mice results in prenatal death, and a recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.

  • Animal-free

 : For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications for Product Family

Specifications

Specifications

  • Catalog No:
  • 10778-506
  • 10778-508
  • 10778-510
  • 10778-512
  • Protein/Peptide Name:
  • Noggin
  • Noggin
  • Noggin
  • Noggin
  • Protein/Peptide Type:
  • Recombinant
  • Recombinant
  • Recombinant
  • Recombinant
  • Protein Function:
  • Cytokines and Growth Factors
  • Cytokines and Growth Factors
  • Cytokines and Growth Factors
  • Cytokines and Growth Factors
  • Species:
  • Mouse
  • Mouse
  • Mouse
  • Mouse
  • Source:
  • E. coli
  • E. coli
  • E. coli
  • E. coli
  • Conjugation:
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Unconjugated
  • Gene ID:
  • 18121 P97466
  • 18121 P97466
  • 18121 P97466
  • 18121 P97466
  • Sequence:
  • MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
  • MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
  • MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
  • MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
  • Protease-free:
  • Y
  • Y
  • Y
  • Y
  • Animal-Free:
  • Y
  • Y
  • Y
  • Y
  • Endotoxin Level:
  • Low
  • Low
  • Low
  • Low
  • Endotoxin Content:
  • >0.1 ng/μg
  • >0.1 ng/μg
  • >0.1 ng/μg
  • >0.1 ng/μg
  • Biological Activity:
  • Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Biological Activity tests can vary. Please refer to the Product CoA for information.
  • Purity:
  • 0.98
  • 0.98
  • 0.98
  • 0.98
  • Form:
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Lyophilized
  • Formulation:
  • Formulation can vary. Please refer to product CoA for information.
  • Formulation can vary. Please refer to product CoA for information.
  • Formulation can vary. Please refer to product CoA for information.
  • Formulation can vary. Please refer to product CoA for information.
  • Molecular Weight:
  • 46.4 kDa
  • 46.4 kDa
  • 46.4 kDa
  • 46.4 kDa
  • Reconstitution Instructions:
  • Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Reconstitution instructions can vary. Please refer to the product CoA for info.
  • Storage Conditions:
  • Store at –20 °C prior to reconstitution.
  • Store at –20 °C prior to reconstitution.
  • Store at –20 °C prior to reconstitution.
  • Store at –20 °C prior to reconstitution.
  • Shipping Temperature:
  • Ambient
  • Ambient
  • Ambient
  • Ambient

Specifications

Product Family Options

Product Information

  • Size
    Origin
    Availability
    Price
  • 10778-506
    100 μg
    US
    Log in for availability
    Log in for availability
    Each (100µG)
    Each (100µG) - $1,785.26
    $1,785.26
    Each (100µG)
       $1,785.26
     
    Supplier Number: AF-250-38-100UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-506
    Protein/Peptide Name
    Noggin
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokines and Growth Factors
    Species
    Mouse
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    18121 P97466
    Sequence
    MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
    Protease-free
    Y
    Animal-Free
    Y
    Endotoxin Level
    Low
    Endotoxin Content
    >0.1 ng/μg
    Biological Activity
    Biological Activity tests can vary. Please refer to the Product CoA for information.
    Purity
    0.98
    Form
    Lyophilized
    Formulation
    Formulation can vary. Please refer to product CoA for information.
    Molecular Weight
    46.4 kDa
    Reconstitution Instructions
    Reconstitution instructions can vary. Please refer to the product CoA for info.
    Storage Conditions
    Store at –20 °C prior to reconstitution.
    Shipping Temperature
    Ambient
  • 10778-508
    250 μg
    US
    Log in for availability
    Log in for availability
    Each (250µG)
    Each (250µG) - $2,636.77
    $2,636.77
    Each (250µG)
       $2,636.77
     
    Supplier Number: AF-250-38-250UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-508
    Protein/Peptide Name
    Noggin
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokines and Growth Factors
    Species
    Mouse
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    18121 P97466
    Sequence
    MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
    Protease-free
    Y
    Animal-Free
    Y
    Endotoxin Level
    Low
    Endotoxin Content
    >0.1 ng/μg
    Biological Activity
    Biological Activity tests can vary. Please refer to the Product CoA for information.
    Purity
    0.98
    Form
    Lyophilized
    Formulation
    Formulation can vary. Please refer to product CoA for information.
    Molecular Weight
    46.4 kDa
    Reconstitution Instructions
    Reconstitution instructions can vary. Please refer to the product CoA for info.
    Storage Conditions
    Store at –20 °C prior to reconstitution.
    Shipping Temperature
    Ambient
  • 10778-510
    500 μg
    US
    Log in for availability
    Log in for availability
    Each (500µG)
    Each (500µG) - $4,519.01
    $4,519.01
    Each (500µG)
       $4,519.01
     
    Supplier Number: AF-250-38-500UG
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-510
    Protein/Peptide Name
    Noggin
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokines and Growth Factors
    Species
    Mouse
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    18121 P97466
    Sequence
    MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
    Protease-free
    Y
    Animal-Free
    Y
    Endotoxin Level
    Low
    Endotoxin Content
    >0.1 ng/μg
    Biological Activity
    Biological Activity tests can vary. Please refer to the Product CoA for information.
    Purity
    0.98
    Form
    Lyophilized
    Formulation
    Formulation can vary. Please refer to product CoA for information.
    Molecular Weight
    46.4 kDa
    Reconstitution Instructions
    Reconstitution instructions can vary. Please refer to the product CoA for info.
    Storage Conditions
    Store at –20 °C prior to reconstitution.
    Shipping Temperature
    Ambient
  • 10778-512
    1 mg
    US
    Log in for availability
    Log in for availability
    Each (1mg)
    Each (1mg) - $7,569.16
    $7,569.16
    Each (1mg)
       $7,569.16
     
    Supplier Number: AF-250-38-01M
    Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
    Specifications:
    More
    Specifications
    Cat. No.
    10778-512
    Protein/Peptide Name
    Noggin
    Protein/Peptide Type
    Recombinant
    Protein Function
    Cytokines and Growth Factors
    Species
    Mouse
    Source
    E. coli
    Conjugation
    Unconjugated
    Gene ID
    18121 P97466
    Sequence
    MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC
    Protease-free
    Y
    Animal-Free
    Y
    Endotoxin Level
    Low
    Endotoxin Content
    >0.1 ng/μg
    Biological Activity
    Biological Activity tests can vary. Please refer to the Product CoA for information.
    Purity
    0.98
    Form
    Lyophilized
    Formulation
    Formulation can vary. Please refer to product CoA for information.
    Molecular Weight
    46.4 kDa
    Reconstitution Instructions
    Reconstitution instructions can vary. Please refer to the product CoA for info.
    Storage Conditions
    Store at –20 °C prior to reconstitution.
    Shipping Temperature
    Ambient
   
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