Human Recombinant Nanog-TAT (from E. coli)
About this item
Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, that helps maintain pluripotency and self renewal via a STAT3-independent pathway. The introduction of nanog, along with Sox2, Oct4, and Lin28, into primary human fibroblasts was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology and gene expression. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary, as well as transformed, cells. Recombinant Human Nanog-TAT is a 36.1 kDa protein, which is synthesized as a 304 amino acid polypeptide plus a 13- residue C-terminal TAT peptide.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
6 Options Available Below
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, that helps maintain pluripotency and self renewal via a STAT3-independent pathway. The introduction of nanog, along with Sox2, Oct4, and Lin28, into primary human fibroblasts was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology and gene expression. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary, as well as transformed, cells. Recombinant Human Nanog-TAT is a 36.1 kDa protein, which is synthesized as a 304 amino acid polypeptide plus a 13- residue C-terminal TAT peptide.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 10772-588
- 10772-590
- 10772-592
- 10772-594
- 10772-596
- 10772-598
- Protein/Peptide Name:
- Nanog-TAT
- Nanog-TAT
- Nanog-TAT
- Nanog-TAT
- Nanog-TAT
- Nanog-TAT
- Protein Synonyms:
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- NANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8
- Protein/Peptide Type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Species:
- Human
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- 79923 Q9H9S0
- 79923 Q9H9S0
- 79923 Q9H9S0
- 79923 Q9H9S0
- 79923 Q9H9S0
- 79923 Q9H9S0
- Sequence:
- SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR - SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR - SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR - SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR - SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR - SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRR
- Protease-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Endotoxin Level:
- Low
- Low
- Low
- Low
- Low
- Low
- Endotoxin Content:
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- Biological Activity:
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Purity:
- 0.95
- 0.95
- 0.95
- 0.95
- 0.95
- 0.95
- Form:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Formulation:
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Molecular Weight:
- 36.1 kDa
- 36.1 kDa
- 36.1 kDa
- 36.1 kDa
- 36.1 kDa
- 36.1 kDa
- Reconstitution Instructions:
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage Conditions:
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Shipping Temperature:
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
Specifications
Product Family Options
Product Information
- SizeOriginAvailabilityPrice
- Supplier Number: 120-21B-5UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-588Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient - Supplier Number: 120-21B-20UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-590Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient - Supplier Number: 120-21B-100UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-592Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient - Supplier Number: 120-21B-250UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-594Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient - Supplier Number: 120-21B-500UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-596Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient - Supplier Number: 120-21B-1MGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10772-598Protein/Peptide NameNanog-TATProtein SynonymsNANOGP1|Putative homeobox protein NANOGP8|NANOG|PN8Protein/Peptide TypeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID79923 Q9H9S0SequenceSVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE
NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA
PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS
DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDVGGYGRK KRRQRRRProtease-freeYEndotoxin LevelLowEndotoxin Content>0.1 ng/μgBiological ActivityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular Weight36.1 kDaReconstitution InstructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage ConditionsStore at –20 °C prior to reconstitution.Shipping TemperatureAmbient
Recommendations will be personalized based on your shopping preferences only if you have given your consent by enabling "Enhance my Shopping Experience" on the "Personal Info page".
Otherwise, you will receive generic recommendations.



