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Specifications
- Antibody Type:Primary
- Antigen Name:Aldo-Keto Reductase Family 7, Member A2
- Antigen Symbol:AKR7A2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Environmentally Preferable:
- Cross Adsorption:No
- Form:liquid
- Antigen Synonyms:AFB1 aldehyde reductase 1|AFB1 AR1|AFB1AR1|SSA reductase|AFB1-AR 1|Aflatoxin aldehyde reductase|AFAR1|AFAR|Akr7a2|Aflatoxin B1 aldehyde reductase member 2|Aldo keto reductase family 7 member A2|ARK72_HUMAN|Succinic semialdehyde reductase.|Aflatoxin beta1 aldehyde reductase|Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase|AKR7|Aldoketoreductase 7|Aldo keto reductase family 7|Aiar
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage Temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10259-814
- Supplier no.:BS-11706R
Specifications
About this item
The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: SSA reductase/AKR7A2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat