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Anti-CHEK1 Rabbit Polyclonal Antibody
Anti-CHEK1 Rabbit Polyclonal Antibody
Catalog # 10251-766
Supplier:  Bioss
Anti-CHEK1 Rabbit Polyclonal Antibody
Catalog # 10251-766
Supplier:  Bioss
Supplier Number:  BS-11226R

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    Checkpoint Kinase 1
  • Antigen Symbol:
    CHEK1
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    100 µg
  • Cross Adsorption:
    No
  • Form:
    liquid
  • Antigen Synonyms:
    kinase Chk1|CHK1|EC 2.7.11.1|CHEK1
  • Modification:
    Ser296
  • Storage Buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
  • Storage Temperature:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping Temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Cat. No.:
    10251-766
  • Supplier no.:
    BS-11226R

Specifications

About this item

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200

Type: Primary
Antigen: CHEK1
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: